From gilbertd from net.bio.net Thu Feb 3 15:23:27 2011 From: gilbertd from net.bio.net (Don Gilbert) Date: Thu Feb 3 15:24:30 2011 Subject: [Arthropod] "new" Genome of Daphnia pulex published Message-ID: <201102032023.p13KNRB28604@net.bio.net> Here is another arthropod genome, finally in press after several years of wrestling with this data. -- Don The Ecoresponsive Genome of Daphnia pulex http://www.sciencemag.org/content/331/6017/555.abstract Science 4 February 2011: Vol. 331 no. 6017 pp. 555-561 DOI: 10.1126/science.1197761 We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200 megabases and contains at least 30,907 genes. The high gene count is a consequence of an elevated rate of gene duplication resulting in tandem gene clusters. More than a third of Daphnia's genes have no detectable homologs in any other available proteome, and the most amplified gene families are specific to the Daphnia lineage. The coexpansion of gene families interacting within metabolic pathways suggests that the maintenance of duplicated genes is not random, and the analysis of gene expression under different environmental conditions reveals that numerous paralogs acquire divergent expression patterns soon after duplication. Daphnia-specific genes, including many additional loci within sequenced regions that are otherwise devoid of annotations, are the most responsive genes to ecological challenges. See also genome companion papers at http://www.biomedcentral.com/series/Daphnia ~ -- d.gilbert--bioinformatics--indiana-u--bloomington-in-47405 -- gilbertd@indiana.edu--http://marmot.bio.indiana.edu/