IUBio GIL .. BIOSCI/Bionet News .. Biosequences .. Software .. FTP

[Arthropod] EvidentialGene update: Gene-omes from mRNA-seq assembly overtake genome gene-predictions

Don Gilbert via arthropod%40net.bio.net (by gilbertd from net.bio.net)
Thu Feb 6 21:05:49 EST 2014

EvidentialGene update: Gene-omes from mRNA-seq assembly overtake genome gene-predictions

An existing dogma in genome projects, that quality of a gene set is dependent on the 
quality of the genome assembly, is no longer accurate.

mRNA-seq assembly now does as well or better than genome-gene modelling.
Both together, with methods that emphasize mRNA-seq assembly and address 
genome-assembly and prediction errors, do the best.

Learn more of this at http://arthropods.eugenes.org/EvidentialGene/
with summary of methods, results in this poster document

A recent plant gene set comparison puts Cacao tree genes of the Mars/USDA project,
built with Evigene methods at top for plant gene-set completeness. 
For banana, mRNA-only genes are equal to genome-genes.

A forecoming killifish gene set using Evigene methods is at top of
10 fish gene sets for completeness, above sets from NCBI and Ensembl
gene modelling methods.

A still-in-progress Daphnia magna gene set is near/at top of arthropod
gene set completeness, and mRNA-only gene assemblies for zebra tick,
a beetle and other arthropods  are good shows versus genome-gene sets.

The Evigene mRNA-assembly pipeline software is working well enough in
other people's hands now, and they are finding same sorts of results
that I find:
using this

-- Don Gilbert

More information about the Arthropod mailing list

Send comments to us at archive@iubioarchive.bio.net