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Philipp Bucher's euk promotor weight matrices

Steve Thompson: VADMS genetics THOMPSON at WSUVMS1.CSC.WSU.EDU
Wed Sep 23 12:15:45 EST 1992


Hello netlanders -

Has anyone heard of or done for themselves the conversion of Dr. Bucher's
weight matrix descriptions of eukaryotic promoter elements to GCG Consensus.Csn
format?  These matrices are described in _J._Mol._Biol._ (1990) 212: 563-578. 
I am teaching a course this semsester in computer techniques in molecular
biology and would very much like to use this data to illustrate the power of
weight matrix approaches versus simple one-dimensional pattern matching.  I
realize that the conversion probably is not that difficult, however, if it has
already been done, it sure would save me some time.

While on this topic, I've searched LIMB to see if there is a database of weight
matrix consensus descriptions and found nothing.  Have any of you heard of a
collection of this type of data?  I do have access to Dr. Bucher's EPD database
but am especially interested in weight matrix patterns.

					Thanks in advance, Steve Thompson

                              Steven M. Thompson
            Consultant in Molecular Genetics and Sequence Analysis
VADMS (Visualization, Analysis & Design in the Molecular Sciences) Laboratory
           Washington State University, Pullman, WA 99164-1224, USA
          AT&Tnet:  (509) 335-0533 or 335-3179  FAX:  (509) 335-0540
                  BITnet:  THOMPSON at WSUVMS1 or STEVET at WSUVM1
                   INTERnet:  THOMPSON at wsuvms1.csc.wsu.edu





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