Paula E. Burch writes:
>Can anyone point me to a program for performing hydrophobic cluster
>analysis of protein sequences? I've read mentions of HCA plot, written
>in Fortran 77, and also HCABAND in BASIC.
>>The reference is C. Gaboriaud, V. Bissery, T. Benchetrit and J.P. Mornon's
>Hydrophobic cluster analysis: an efficient new way to compare and analyse
>amino acid sequences, FEBS Letters 224(1):149-155 (1987).
(some stuff deleted)
You can find a pretty good implementation of the HCA plot, although b/w only,
as a menu item in the freeware macintosh program called DNAid, available
I hope it helps.
Jean-Louis Ruelle Dept of Molecular Biology
SmithKline Beecham Biologicals jlr%rxvgen.dnet at smithkline.com
Rue de l'Institut, 89
1330 Rixensart, Belgium.