In article <BRIANF.92Sep21172418 at dna.uvm.edu>, brianf at dna.uvm.edu (Brain Foley) writes:
> I am looking for a program (Mac, DOS, or VMS) that will help
> me draw a circular (or linear) map of DNA, given a list of the
> restriction fragment sizes that are observed upon single and
> multiple-enzyme digests.
> I have looked in the IBMPC and MAC subdirectories of the
> MOLBIO directory of FLY.BIO.INDIANA.EDU FTP site. I did not see what
> I wanted there, but I may have missed something.
I must heartily recommend a package called RESOLVE for PC, available from Prof.
Eric Harley, UCT Medical School, PO Observatory 7925, South Africa (or, more
obviously for this forum, harley at chempath.uct.ac.za or @uctvax.uct.ac.za).
This assists in mapping in that it tells you when the (or a) map is obtainable
from the data; it also tells you how MANY maps can be made from the same data
given different errors in measurement of band size! It can be used as a map
database, and even to compare any number of maps in terms of phylogenetically
informative sites, or proportion of sites shared. Costs US$100 from him
direct (I have no interest, I just like the package).
| | |
| Ed Rybicki | Now you've got the hang of it |
| Dept Microbiology | There's nothing you can't do with it |
| University of Cape Town | If you're very into it |
| PB Rondebosch 7700 | You can't go wrong.... |
| South Africa | |
| fax 27 21 650 4023 | - Mad John |
|ed at micro.uct.ac.za | (Ogden's Nut-Gone Flake, Small Faces) |