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T=cell epitope prediction

Dan Jacobson danj at welchgate.welch.jhu.edu
Tue Mar 9 14:23:59 EST 1993

In article <1993Mar9.150715.6544 at gserv1.dl.ac.uk> bss2aj at surrey.ac.uk (Alan Jennings) writes:
>Doe anyone know of any software prefaraly PD) which can be used for
>prediciting Th-cell epitopes on protein sequences?

Hmm, seems like I just answered a similar question.  

Three programs which come to mind are Epiplot, Tsites, and Seqaid.
Epiplot and Tsites are programs devoted specifically for epitope
prediction, Seqaid is a general sequence utlity program with several
functions, one of which is epitope prediction.  Seqaid and Epiplot are
for PCs (DOS), Tsites has a Mac version and probably a DOS version.

You can ftp Epiplot from:

Host evolution.bchs.uh.edu

    Location: /pub/gene-server/dos
           FILE -rwxr--r--     129317  Sep 16 1991  epiplot.uue

You can ftp seqaid from:

Host fly.bio.indiana.edu

    Location: /molbio/ibmpc
           FILE -rw-r--r--     324175  May 14 1991  seqaidfd.uue

Host genbank.bio.net

    Location: /pub/dos
           FILE -rw-rw-r--       6167  Oct 26 1989  seqaid.doc
           FILE -rw-rw-r--     324175  Jul 14 1989  seqaidfd.uue

Host nic.funet.fi

    Location: /pub/sci/molbio/msdos
           FILE -rw-r--r--     251259  Feb  3 00:00  seqaid.exe
           FILE -rw-rw-r--     305448  Jun 23 1991  seqaid37.shar
           FILE -rw-r--r--      73370  Feb  3 00:00  seqaidfd.exe

There is no ftp site for Tsites that I know of, you can obtain it
for free by writing to:

MedImmune, Inc
19 Firstfield Rd.
Gaithersburg, MD 20878  (USA)

Best of luck,

Dan Jacobson

danj at welchgate.welch.jhu.edu

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