In article <1.4467.570.0NB42ACB at execnet.com>,
peter.foiles at execnet.com (Peter Foiles) writes:
>>I would like some information on PC based software that is available for
> searching the Genbank database on CD-ROM. We have been using the IBI
>Pustel program but it apparently is not compatible with the Genbank data
>on CD-ROM. The commercial software we have found so far has been
>prohibitively expensive. Any suggestions would be greately appreciated.
>>==Peter Foiles, PhD==
I would recommend that you use the NCBI resources. There is a
great CD-ROM Genbank/Medline suite called ENTREZ that is available
for the price of the plastic alone. Updates are available quarterly
I think. For that up-to-the-minute search, the Genbank resource can
be searched by e-mail using BLAST and interesting sequences can be
retrieved using RETRIEVE. Both of these are free. For information
on BLAST and RETRIEVE, send a "help" message to:
BLAST at ncbi.nlm.nih.gov or RETRIEVE at ncbi.nlm.nih.gov
There is also a great local homology program for protein sequences
called MACAW that is also available from NCBI by FTP. I strongly
urge people to use these valuable resources and acknowledge them
properly. A number of years ago there was a useful BIONET resource
that was discontinued by the NIH and not enough people complained.
Use it or lose it...