I would like to announce the availability of a new database dedicated
to keeping data on G-protein--coupled receptors in one place.
Todate there are over 900 entries in GenBank and the other databases.
These entries have been collected and added to and classified.
The classifications and the database itself is described in a
manuscript which is available electronically.
GCRDb is available in a limited version today, more data including
mutant and ligand data are in preparation.
GCRDb is available for anonymous FTP access from two sites:
Receptor.MGH.Harvard.edu (220.127.116.11) in /pub/GCRDb
NCBI.NLM.NIH.gov (18.104.22.168) in repository/gcrdb
| GGGGGG CCCCCC RRRRRRRR |
| G G Protein C Coupled R Receptor - DATABASE |
| G C R R |
| G GGG C RRRRRRRR |
| G G C C R R |
| GGGGGG CCCCCC R R |
| Including several other unknown seven transmembrane segment |
| containing proteins |
Collected and Maintained by:
Lee F. Kolakowski, Jr (aka Frank)
Massachusetts General Hospital
Charlestown Navy Yard / Building 149
Boston, MA 02129
lfk at receptor.mgh.harvard.edu (main-email)
kolakowski at helix.mgh.harvard.edu (email)
lfk at eastman1.mit.edu (email)
Release 1.0 $Revision: 1.5 $
This is the protein portion of the G-protein-coupled receptor
GCRDb is under continual development, and new data is being added
This is meant to be used as a search database for people working
on cloning and characterizing new GCRs. Other data is being added to
the database, and will eventually be released as a complete package.
GCRDb is being developed without formal funding. Contributions
will be accepted to defray hardware and programming costs.
This is provided without any implied or otherwise stated
guarantee as to the completeness or correctness of the data.
GCRDb is protected by a copyright.
Copyright (c) 1990, 1991, 1992, 1993, 1994 by Lee F. Kolakowski, Jr.
All rights reserved.
Permission is granted to copy and redistribute this database so long
as it is unmodified and the copyright remains intact. I'd appreciate
it if you told me about any redistribution, but that's not strictly
Files in this directory are:
GCRDb.README - This file
GCRDb.list - A list of entries in GCRDb
GCRDb.pep - Data file in PEARSON - Fasta format
GCRDb.refer - References to sequences in GCRDb in Refer format
GCRDb_Fig1.hqx - Figure 1 for GCRDb paper in MacDraw
GCRDbpaper.ps - PostScript of the GCRDb manuscript
The paper in the archive is in press
Please cite as:
Kolakowski, L.F., (1994) GCRDb: A G-protein--coupled receptor
database, Receptors and Channels: The International Journal of
Receptors, Channels and Transporters, In press.
Distribution of this manuscript is limited to personal use. The paper
is copyright by Harwood Academic Press.
O Email: lfk at receptor.mgh.harvard.edu O
O kolakowski at helix.mgh.harvard.edu O
O lfk at eastman1.mit.edu O
O US Mail: Lee F. Kolakowski Renal Unit, 8th Flr. O
O Massachusetts General Hospital Charlestown Navy Yard O
O 149 13th Street FAX : 1-617-726-5669 O
O Charlestown, MA 02129 Phone AT&T: 1-617-726-5666 O
O The home of the G-Protein-Coupled Receptor Database (GCRDb) O