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DB searching with short peptides from phage display

Darek Kedra darked at my-deja.com
Thu Aug 9 03:58:00 EST 2001


Dear All,

I've got short, 9-15 AA long peptide sequences from phage display.
These are "random" sequences which happen to interact with a target.
The next step is to find if something similar exist in nature.
I wonder if you can recommend "the best" program/algoritm for doing
it.
I've used blast (blastp / nr database  and tblastn / est db) but
finding anything meaningful in 500+ weak matches is a tall order.

Thank you in advance.
Greetings

Darek Kedra

d a r k e d  at  m y -d e j a . c o m

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