This is a quick pointer to two Web utilities which may be of interest
to users of this group. Since the announcement in July, additional
features have been incorporated and miscellaneous bugs have been fixed.
You can now "cut and paste" into the forms - the (Frontier) CGIs will
automatically weed out carriage returns, line feeds, spaces, etc.
Oligo Vital Stats
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URL: http://cy-mac.welc.cam.ac.uk/oligo_form.html
Accepts an oligo sequence and sends back useful information on it such as
length, composition, percentage GC content, molecular mass, melting point
(calculated by 2 methods), and various molar and concentration equivalents.
The oligo can (optionally) be given a name, and the salt concentration can
be changed.
Bipartite Nuclear Localisation Sequence Locator
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URL: http://cy-mac.welc.cam.ac.uk/biploc_form.html
Runs a search through an amino acid sequence, looking for bipartite nuclear
localisation sequences (pair of basics + spacer of any 10 amino acids +
cluster of 3/5 basics, Robbins, et al., (1991) Cell 64, 615-623). Options
include a choice of spacer length, and also two search methods (Faster and
More Comprehensive).
I hope you find these useful, and would welcome any comments and suggestions.
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