Version 2.0 of the Organelle Genome Database (GOBASE), which provides
a powerful tool for mitochondrial gene and genome research, has been
released.
The GOBASE database currently contains
* all mitochondrial nucleic acid and deduced protein sequences,
obtained from the NCBI Entrez database
* extract functions for DNA and protein sub-sequences (coding region,
gene, exon, intron, etc.)
* taxonomic information extracted from the NCBI Taxon database
* standardized gene names and product names, assigned by the GOBASE
biology experts
* basic information about gene products such as type, function,
enzyme complex
* hyperlinks to the Entrez/NCBI database, allowing lookups,
neighbors etc
* hyperlinks to the intron (Gutell) and ribosomal RNA secondary
structure (Gutell, Schnare and Gray) databases
* hyperlinks to the MendelDB, a database of designations for
sequenced plant genes
* hyperlinks to the ENZYME and EcoCyc enzymatic databases
* hyperlinks to the collections of mitochondrial genetic maps
of the Organelle Genome Megasequencing Program (OGMP) and the
Fungal Mitochondrial Genomes Project (FMGP)
* hyperlinks to the Protist Image Database (PID).
In addition to tying together the mitochondrial (and soon also
chloroplast) sequence data that have been difficult to locate
due to name inconsistencies and various errors, GOBASE allows highly
sophisticated queries including the use of search criteria such
as general function of product, taxonomic group, complete genome
sequence, genetic code or, in near future, gene name synonyms.
A taxonomic grouping in addition to that of the NCBI taxonomic
scheme has been established, to better reflect current views.
Most importantly, the majority of data contained in GOBASE have
been verified and rectified by experts, especially with respect
to the consistency of gene and product nomenclature.
For more details, see
http://megasun.bch.umontreal.ca/gobase/gobase2.html
For further information or comments, please email to
gobase at megasun.bch.umontreal.ca
The GOBASE team
Gertraud Burger Implementation by:
Michael W. Gray Maria Korab-Laskowska
Franz B. Lang Pierre Rioux
Tim Littlejohn Nicolas Brossard