---------- Forwarded message ----------
From: Dmitrij Frishman <frishman at reindeer.mips.biochem.mpg.de>
Dear colleagues,
we are pleased to announce the availability of a new WWW
server devoted to computational analysis of complete genomes.
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PEDANT: Protein Extraction, Description, and ANalysis Tool
http://pedant.mips.biochem.mpg.de/frishman/pedant.html
Features:
- Seven complete and two partial genomic sequences analyzed so far:
S.cerevisiae
M.genitalium
M.pneumoniae
M.jannaschii
Synechocystis sp.
H.influenzae
E.coli
B.subtilis (fragment)
S.solfataricus (fragment)
- Exhaustive functional and structural classification of
the predicted open reading frames from fully sequenced
genomes using a combination of sequence comparison and
prediction techniques
- Functional assignment of ORFs on the basis of FASTA2
similarity searches supplemented by detection of PROSITE
patterns and motifs and comparisons with conserved sequence
blocks
- Automatic attribution of sequences with significantly related
PIR entries to one of the PIR super-families
- Functional classification of gene products through similarity
searches against several curated master gene sets from
bacteria and yeast with manually assigned functional classes
- Extraction of available 3D information through Smith-Waterman
similarity comparisons of every sequence with the STRIDE
database of secondary structure assignments
- Secondary structure and transmembrane region predictions
- Detection of low-complexity and coiled coil regions
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Dmitrij Frishman and Hans-Werner Mewes
Munich Information Centre for Protein sequences
Max-Planck-Institut f. Biochemie/GSF
http://www.mips.biochem.mpg.de
