ProtComp - Version 4: Program for Identification of sub-cellular localization
of Eukaryotic proteins: Animal/Fungi - Plants
NEW ProtComp is available for public usage at: http://www.softberry.com/http://www.softberry.com/protein.html
ProtComp: Current, fourth release of ProtComp developed using
COMBINATION of database analysis of similar proteins and NEURAL NET
recognizers separately trained for Animal/Fungi and Plant proteins.
This separation is improving the recognition accuracy, which is
for major compartments (such as plasma membrane, nuclear,
extracellular) achives >90% level.
The program initially searches our database of proteins
with known sub-cellular location and defines the location the same as
for protein having significant similarity. If such similarity is
absent we use complex neural-network recognizers, which identify
probability of the subcellular localization in nucleus, plasma
membrane, extracellular, cytoplasmic, mitochondrial, chloroplast,
endoplasmic reticulum, peroxisomal, lysosomal or Golgi compartments.
Example of Output results:
Presents scores for Similar protein, different networks and the final
conclusion.
protcompan Mon Jan 29 02:38:30 EST 2001
ProtComp Version 3. Identifying sub-cellular location (Animals&Fungi)
Seq name: P426
Significant similarity by DBSCAN-P - Location:Cytoplasmic S=12980
Predicted by Neural Nets - Cytoplasmic with score 1.7
Integral Prediction of protein location: Cytoplasmic with score 2.6
Location weights: DBSCAN-P / Neural Nets / Integral
Nuclear 554.0 / 1.18 / 0.11
Plasma membrane 0.0 / 0.98 / 0.00
Extracellular 0.0 / 0.76 / 0.00
Cytoplasmic 12980.0 / 1.67 / 2.60
Mitochondrial 0.0 / 0.73 / 0.00
Endoplasm. retic. 0.0 / 0.62 / 0.00
Peroxisomal 0.0 / 0.67 / 0.00
Lysosomal 0.0 / 0.27 / 0.00
Golgi 0.0 / 0.83 / 0.00
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