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Sigfind, version 2.1 for eukaryotes

Martin Reczko reczko at web.de
Fri Mar 8 10:50:27 EST 2002

Synaptic is pleased to announce a new version
of the signal peptide prediction server,
now for all EUKARYOTIC signal peptides at

The new version (2.1) for eukaryotes is trained with
fivefold crossvalidation on 1011 eukaryotic signal peptides
and 820 non-secretory eukaryotic proteins. Predictions on the
test sets have an average Mathews correlation coefficient of 0.98.

The previous version of SIGFIND (2.07), trained with HUMAN
proteins only, has been used by many users also for other eukaryotes.
When tested on the eukaryotic data, the Mathews correlation
for the predictions of SIGFIND 2.07 is 0.95.

Due to the larger training and test sets and the better
performance, we recommend the new version for
all eukaryotic sequences.

- Run Sigfind on your own PC:

 You can get Sigfind 2.1 to run on your own PC.
 The Sigfind Web-CGI and the offline version
 are available for x86-PCs running Linux or MS-Windows.
 Send an email to mailto:synaptic_ltd at yahoo.de to get
 information about the license fee.

 Martin Reczko
 Synaptic Ltd

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