The E-CAI server is a web-application and an
executable program that calculates the expected value of the Codon Adaptation
Index (CAI) for a set of query sequences by generating random sequences with
similar G+C content and amino acid composition to the input. This expected CAI
therefore provides a direct threshold value for discerning whether the
differences in the CAI value are statistically significant and arise from the
codon preferences or whether they are merely artifacts that arise from internal
biases in the G+C composition and/or amino acid composition of the query
sequences.
E-CAI is freely accessible at
http://genomes.urv.cat/CAIcal/E-CAI
For more details see the article Puigbo P,
Bravo IG and Garcia-Vallvé S. E-CAI: a novel server to estimate an expected
value of Codon Adaptation Index (eCAI). BMC Bioinformatics 2008, 9:65
--------------------------------------------------------------------------------------------------------------------
Dr. Pere Puigbò Avalos, PhD
Evolutionary Genomics Group,
Biochemistry and Biotechnology Department,
Rovira i Virgily University.
C/Marcel·lí domingo s/n. 43007. Campus Sescelades. Tarragona.
Phone: 0034.977.55.84.86
Web Page: http://genomes.urv.cat
E-mail: ppuigbo from urv.cat
--------------------------------------------------------------------------------------------------------------------
Visit:
* HEG-DB at http://genomes.urv.cat/HEG-DB
* OPTIMIZER at http://genomes.urv.cat/OPTIMIZER
* TOPD/FMTS at http://genomes.urv.cat/topd
--------------------------------------------------------------------------------------------------------------------
