ANNOUNCING THE THIRD RELEASE OF THE WHITEHEAD
INSTITUTE/MIT GENOME CENTER GENETIC MAP OF THE MOUSE
Release Three of the Whitehead Institute/MIT Genome Center Genetic Map
of the Mouse is now available. This map consists of randomly-chosen
simple sequence length polymorphisms (microsatellites) that can be
analyzed using the polymerase chain reaction, as described in
Dietrich, W., et al., Genetics 131:423-447 (1992).
Currently the released map contains 1524 markers. The markers fall
into 20 linkage groups spanning approximately 1400 cM with an average
spacing of less than 1 cM.
This data can be obtained in two different ways.
1. Via anonymous ftp to genome.wi.mit.edu. Log in as "anonymous" and
use your e-mail address as password. The release can be found in the
directory /distribution/mouse_sslp_release/july93/. The file "README"
describes the file format and gives other information about the map.
2. Via internet e-mail using a database e-mail server. Using this
service you can obtain locus and assay names of mapped SSLPs, the
forward and reverse primer sequences, the genotypes of the loci on the
mapping cross, the sizes of the PCR products on selected standard
inbred strains, and other useful information. The database can be
queried for markers meeting a number of different criteria. For
example, you can ask for markers by name, by chromosome, or by
position on the map. You can even request a list of markers that are
polymorphic between two mouse strains.
To obtain copies of the most current query forms, send a message to
"genome_database at genome.wi.mit.edu" with either a subject line or
body text of "help". You will receive instructions and a query form by
return mail. Just fill out the form, send it to
"genome_database at genome.wi.mit.edu", and the answer to your query will
be mailed back automatically.
This project is an ongoing one. As new markers are added to the map
they will be released on a quarterly basis on approximately the
following schedule:
1 October 1993
1 January 1994
1 April 1994
1 July 1994
&c.
Please address questions and comments to me at the address below.
Lincoln Stein
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Lincoln Stein, M.D.,Ph.D. lstein at genome.wi.mit.edu
MIT Genome Center (617) 252-1916
Whitehead Institute for Biomedical Research (617) 252-1902 FAX
9 Cambridge Center
Cambridge, MA 02142
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Lincoln D. Stein
lstein at genome.wi.mit.edu Whitehead Institute, Cambridge, MA
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