Recounting a genetic story
ROGER H. REEVES
Roger H. Reeves is in the Department of Physiology, The Johns Hopkins
University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland
e-mail: rreeves at welch.jhu.edu
The DNA sequence of human chromosome 21, now published, provides indications
that the total number of human genes has been overestimated, and is a valuable
resource for research into Down syndrome.
The sequencing of whole genomes means that genetic information is increasingly
considered in functional rather than structural terms. But for the moment, the
principal structural element of genomes the chromosome remains the
predominant unit by which to measure progress in the Human Genome Project.
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