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Genomics = Genome sequencing??

Athel Cornish-Bowden athel at ir2cbm.cnrs-mrs.fr
Fri May 7 09:57:04 EST 1999


The following was posted by Donald Forsdyke on mol-evol at net.bio.net, but it
seems quite related also to some of our concerns in metabolic control
analysis:

>The leading article in Nature (15th April) is entitled "WAKE UP CALL FOR
>JAPAN'S GENOMICS". On reading further one finds that it is about genome
>sequencing, NOT genomics.

>Of course, one has to have some sequence before one can begin genomics,
>the latter being the STUDY of sequences, and all that this entails
>(bioinformatic and evolutionary analysis for example). But, HOW MUCH
>SEQUENCE IS ENOUGH?

>The techological imperative seems to have taken over again. Give the guys
>some sequencers and a genome, and they will go on and on until the end,
>and then go about looking for MORE genomes. All this requires megabucks
>whether you count in yen or dollars! How sad that so little of this
>funding employed in doing REAL genomics.

I agree with all that. It seems to me that diverting 1% of the investment
that's going into sequencing into paying people to devise better ways of
using the information that emerges from the sequencing would be very
cost-effective.

Athel

Email: athel at ibsm.cnrs-mrs.fr
Site map: http://ir2lcb.cnrs-mrs.fr/~athel/sitemap.htm
Visegrad, April 1999: http://ir2lcb.cnrs-mrs.fr/~athel/meet99.htm
New Beer in an Old Bottle: http://ir2lcb.cnrs-mrs.fr/~athel/buchner.htm
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MCA chapter from my book:
http://ir2lcb.cnrs-mrs.fr/~athel/mcai.htm



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