Odd you should mention this topic because I had a quick look at some newly
published biochemistry text books last weekend and was surprised to see that
after all these years they still proudly spell out very clearly the idea of
the rate-limiting step. I was even more surprised to see the rate-limiting
step boldly announced in the new edition of Lehninger. It makes one wonder
that if there are such blatant misconceptions in one part of the book, how
are we to trust the rest of the material?
Herbert Sauro
Athel Cornish-Bowden <athel at ir2cbm.cnrs-mrs.fr> wrote in message
news:v03007803b562d2ca2ebb@[193.50.234.80]...
> Many of us active in this field have felt frustrated that the standard
> textbooks that biochemistry students around the world read continue to
> repeat the same old nonsense, such as the idea that phosphofructokinase
> controls the glycolytic flux (or is it pyruvate kinase? or hexokinase? or
> all three, as Stryer seems to think?).
>
