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phylogenetic trees

Oliver Hobert hobert at FRODO.MGH.HARVARD.EDU
Tue Jun 4 15:44:13 EST 1996

Hey -
I'm doing multiple sequence alignments with families of sequences from the
worm genome project + cross-species homologs. Using GCG I get nice
alignment but the phylogenetic trees I get with the "distances" and
"growtree" command give very unreliable results (e.g. cross-species
homologues appear in completely divergent branches). Does anybody know how
to either get rid of this problem and/or whether there are any good other
programs to have phylogenetic trees constructed ?
Thanks a lot for a reponse,

Oliver Hobert
Mass. General Hospital
Department of Molecular Biology
Wellman 8
Boston, MA 02114
Fax: 617-726 6893

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