Post-doctoral position at the National Institute of Health to study the
genetics of metal-responsive gene expression in C. elegans
A postdoctoral position is available in the Comparative Genomics group
in the Laboratory of Molecular Toxicology at the National Institute of
Environmental Health Science, NIH., to study the mechanisms by which
transition metals affect transcription in C. elegans. Classic genetic
and reverse genetic approaches will be used to dissect the regulatory
pathways responsible for controlling cadmium-responsive transcription.
The Comparative Genomics group uses a variety of model systems (yeast,
mammalian cell culture, zebrafish and C. elegans) to study stress
response gene expression. Target genes currently under investigation
include metallothioneins (mtl), the cadmium responsive gene family
(cdr), and metal-responsive genes identified using DNA microarrays.
Expertise in C. elegans genetics and molecular biology is strongly
TO APPLY: Submit a cover letter, curriculum vitae, bibliography and the
names of three references by e-mail to Jonathan H. Freedman, Ph.D.
freedma1 at niehs.nih.gov <mailto:freedma1 at niehs.nih.gov>
DHHS/NIH/NIEHS is an Equal Opportunity Employer.
Jonathan H. Freedman, Ph.D.
Investigator, Laboratory of Molecular Toxicology
Environmental Toxicology Program
Division of Intramural Research, National Institute of Environmental
National Institute of Health
Research Triangle Park, NC