A postdoctoral position is available in the Chuang laboratory in the
Division of Developmental Biology at Cincinnati Children's Hospital
Research Foundation. We are interested in understanding the
molecular mechanisms by which neurons differentiate and assemble into
functional circuits, using the small roundworm Caenorhabditis elegans
as an experimental organism (Chuang and Bargmann 2005, Chuang et.
al., 2007). The lab uses a multidisciplinary approach that
integrates genetics, molecular biology, cell biology, biochemistry,
electrophysiology and live imaging to address this question. To
learn more about the lab, please visit
http://www.cincinnatichildrens.org/research/div/dev-biology/fac-labs/chuang/
This position involves the study of a gap junction network that
coordinates left-right neuronal asymmetry. Prior experience in C.
elegans is helpful but not a prerequisite. Applicants should have a
Ph.D. degree (for less than three years) in genetics, cell biology,
molecular biology, neurobiology, biochemistry or similar with
experience in molecular biology techniques. Interested candidates
please send a brief cover letter describing research experience, CV,
and names and contact information of three references to Dr.
Chiou-Fen Chuang at Chiou-Fen.Chuang from cchmc.org.
References:
Chuang, C.-F., VanHoven, M. K., Fetter, R. D., Verselis, V. K., and
Bargmann, C. I. An
innexin-dependent cell network establishes left-right neuronal
asymmetry in C. elegans. Cell, in press.
Chuang, C.-F. and Bargmann, C. I. (2005). A Toll-interleukin 1
repeat protein at the synapse specifies asymmetric odorant receptor
expression via ASK1 MAPKKK signaling. Genes & Dev. 19, 270-281.
(http://www.genesdev.org/cgi/content/full/19/2/270)
--
Chiou-Fen Chuang, Ph.D.
Assistant Professor
Division of Developmental Biology
Cincinnati Children's Research Foundation
3333 Burnet Avenue, ML 7007
Cincinnati, OH 45229-3039
(513) 803-0046 (office)
(513) 636-8117 (lab)
(513) 636-4317 (fax)
Chiou-Fen.Chuang from cchmc.org
