GC-MS analysis of cyclic nucleotides

[Simon Penson]

Dear Netters,

I'm interested in analysing for cGMP in extracts of plants tissue. I will
probably use an RIA kit for more routine work, but I will also need to use
a more unequivocal method at some point. GC-MS would be useful. My
question is: Has GC-MS been used for cGMP determination, and what are the
detection limits for this technique?

I can explain more fully if you think that would be useful!!

Thanks in advance,

Simon.
Simon Penson
Plant Biology
UC Berkeley.
Tel: (510) 642 6084