Hi, I keep getting requests for a staining paraffin sections for macrophages
in particular cases of suspected histiocytic tumors in dogs. What we are
looking for is a marker for macrophages/histiocytes in paraffin sections
which could be used in any species. Is there anyone out there in netland
who is already doing this? My initial thoughts are that an antibody to
myeloperoxidase or alpha 1 anti tryosin might be the way to go but I am
short on time and wonder if anyone has validated such an antibody on paraffin
sections, or for that matter in other species. Most of the commercially
available antibodies such as Mac-1 or Mac-3 do not seem to work on paraffin
sections of canine tissues so I am looking for a more generic marker.
Thanks for any advise.
Regards
BJC - Brian Short people... last to know its
raining, first to know its a flood.
