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Serological Controls in Test Kits

Thierry Leclipteux thierry at stat.fmv.ulg.ac.be
Fri Nov 3 06:54:26 EST 1995


In article <951102140530_96176626 at emout04.mail.aol.com> ,
MHughes77 at aol.com writes:

I know several way to inactivate viruses.  But probably those giving best
results to protect the antigenicity would be  : ß-propiolactone and UV
radiation.  I have to mention that Aujesky virus is not inactivate by
ß-propioloactone but well by UV.  It seems that there is no fixed recipe.
 So do some trials.

I guess that (for human, field at least) control sera must be proven free
of pathogens.  I have to check in my guidelines to know what about it.

As I am also working (part-time) for a diagnostic company in the vet
field, I would like to know if there is any components to stabilize
peroxidase conjugate in a liquid form in order to keep them either
concentrated or ready-to-use in the kits.



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