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glycosylation sequences

Steven Pirie-Shepherd srps at galactose.mc.duke.edu
Thu Aug 29 14:44:43 EST 1996


Edward McSweegan, PhD (EM8P at NIH.GOV) wrote:
: Aside from the single amino acid sights of glycosylation, are there any 
: specific amino acid sequences that signal or suggest points of 
: glycosylation?  I've heard there are some for eukaryotes.  Are there any 
: such sequences for bacteria?

: Thanks

: E. McSweegan

You need to be a bit more specific. there is a very simple sequence that 
is necessary but not sufficient for N-linked glycosylation, and there are 
a variety of concensus sequeences and algorithms that predict mammalian 
O-linked glycosylation. I am not familiar with bacterial sequences, i was 
under the impression (perhaps mistaken) that bugs don;t glycosylate the 
way that Eukaryotes do.


__________________________________________________
Steven Pirie-Shepherd		       		
srps at galactose.mc.duke.edu	        
"Insert your own pithy phrase just about here!"



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