Postdoctoral Position in Maize/Rice Protein Biochemistry and
Proteomics
van Wijk lab, Cornell University, Ithaca, NY, USA.
[1]http://cbsu.tc.cornell.edu/vanwijk/
Experienced Plant Protein Biochemist A postdoctoral position (2-3
years) in Plant Protein Biochemistry and Proteomics in the van Wijk
lab is available to contribute to a collaborative project (Cornell,
Yale and Iowa Universities) sponsored by the NSF-Genome program. This
project concerns a cell-type specific comparative analysis of C3 and
C4 leaf development in Rice, Sorghum and Maize. In leaves of such C4
grasses photosynthetic activities are partitioned between two
morphologically and biochemically distinct bundle sheath (BS) and
mesophyll (M) cells. The objectives are to compare the quantitative
and qualitative patterns of transcripts, proteins, metabolic
activities and anatomy at discrete stages and in specific cell types
in rice (C3), maize and sorghum (C4), and to develop a model of the
regulatory networks governing C4 anatomy and function. These
experimental datasets will be linked by new informatics tools for
comparative transcriptional and proteome analysis, to provide the
foundation for a systems biology approach to understanding C4 biology.
The responsibilities of the postdoc include isolation of subsets of
leaf proteomes (e.g. BS strands), protein separation and proteome
analysis, as well as biological interpretation of these large scale
data sets. Experience in plant protein biochemistry (with a proven
track record) and a strong interest in plant metabolism, leaf growth,
development and systems biology is required. Experience with
nanoLC-Electrospray tandem Mass Spectrometry (e.g. LTQ, Q-TOF or
LTQ-Orbitrap) is beneficial. The postdoc will work closely together
with other team members, including mass spectrometry specialists and
bioinformaticians. Salary will be commensurate with experience with
generous employee benefits according the Cornell Human Resource
Office.
Review of applications will begin immediately, and continue until the
position is filled. Application Instructions: Send your curriculum
vitae, a statement of research interests and career goals,
representative publications, and three letters of reference by email
to: [2]kv35 from cornell.edu Klaas J. van Wijk, Associate Professor, Dept
of Plant Biology, Cornell University, Ithaca, NY 14853, USA; tel
+1-607-255-3664; [3]http://cbsu.tc.cornell.edu/vanwijk/
Relevant papers:
Majeran W., Zybailov B., Ytterberg A.J., Dunsmore J., Sun Q.and van
Wijk K.J. (2008) Consequences of C4 differentiation for chloroplast
membrane proteomes in maize mesophyll and bundle sheath cells. Mol
Cell Proteomics - pre-publication online -
Covshoff S., Majeran W., Liu P., Kolkman J.M., van Wijk K.J.and
Brutnell T.P. (2008) Deregulation of maize c4 photosynthetic
development in a mesophyll cell-defective mutant. Plant Physiol 146:
1469-1481.
Majeran W., Cai Y., Sun Q.and van Wijk K.J. (2005) Functional
Differentiation of Bundle Sheath and Mesophyll Maize Chloroplasts
Determined by Comparative Proteomics. The Plant Cell 17: 3111-3140.
Klaas J. van Wijk
Associate Professor
Director of Graduate Studies (DGS) for the Field of Plant Biology
Dept of Plant Biology
332 Emerson Hall
Cornell University
Ithaca, NY 14853, USA
tel +1-607-255-3664
[4]http://cbsu.tc.cornell.edu/vanwijk/
References
1. 3D"http://cbsu.tc.cornell.edu/vanwijk/"
2. 3D"mailto:kv35 from cornell.edu"
3. 3D"http://cbsu.tc.cornell.edu/vanwijk/"
4. 3D"http://cbsu.tc.cornell.edu/vanwijk/"