In article <32drr4$8l7 at news.mic.ucla.edu>, arne at hodgkin.mbi.ucla.edu (Arne Elofsson) writes:
|>Fred Cohen showed a long time ago that packing of a four helical boundle
|>|>1. Presnell SR; Cohen FE.
|> Topological distribution of four-alpha-helix bundles.
|> Proceedings of the National Academy of Sciences of the United States of
|> America, 1989 Sep, 86(17):6592-6.
|>|>and several other references
|>Was this about building FXN and MBD? Or better said: the packing of the helices
of these proteins. If so: He made several modells given the EXACT secondary
structure (100%) and he made several modells differing quite a lot from
the native folding.
|>>>By the way, I don't think 65% is a good result.
|>>|>Rost and sander showed that proteins are approximately 82% correct
|>(within a family) So it is not that bad.
|>I cannot agree, Chou and Fassmann also result in about 60 to 65%. And by the
way, random "prediction" results in 50%. So 65% is a VERY little but not a lot.
Hannes
===========================================================================
Floeckner Hannes e-mail: floeckn at wst.edvz.sbg.ac.at
Inst.f. Chemie und Biochemie
Universitaet Salzburg
Jakob-Haringerstr. 1
A-5020 Salzburg
AUSTRIA - EUROPE
