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Protein structure databases?

Steve Gardner steve at gardner.demon.co.uk
Wed Aug 24 01:35:43 EST 1994

In article: <cc37-210894182902 at>  cc37 at cornell.edu (CC) writes:
> Hi --
>       Do there exist databases that have information about the secondary
> structure, active sites, mutations that disrupt function, etc. of
> evolutionarily conserved proteins?  I am particularly looking for
> information on subunits of ATP synthase FO and cytochrome c oxicase, as
> well as other H+ membrane pore-forming comlexes.  Any information would be
> greatly appreciated -- please send e-mail to cc37 at cornell.edu.  Sorry if
> this is a FAQ, but I couldn't find the archive.
>       Thanks!
>                                                -- CC

The Iditis relational database of protein structure contains over 500 fields of derived
protein structure data, including secondary structure, active site data, and 
functional motif information.  The database describes the 2000 known proteins completely
and allows you to identify and compare complex motifs easily. It is designed
specifically to allow users to ask questions of about potential effects of changes
made to the structure of a protein in key regions of structure.  Iditis comes out of
Prof. Janet Thornton's lab at University College London.

For more information see the review article
in Chemical Design Automation News (Thornton & Gardner) vol. 8, no. 4 pg. 18.

Steve Gardner

steve at gardner.demon.co.uk

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