In <414428490wnr at gardner.demon.co.uk>, steve at gardner.demon.co.uk (Steve Gardner) writes:
>In article: <cc37-210894182902 at 132.236.171.160> cc37 at cornell.edu (CC) writes:
>>>> Hi --
>> Do there exist databases that have information about the secondary
>> structure, active sites, mutations that disrupt function, etc. of
>> evolutionarily conserved proteins? I am particularly looking for
>>The Iditis relational database of protein structure contains over 500 fields of derived
>protein structure data, including secondary structure, active site data, and
>functional motif information. The database describes the 2000 known proteins completely
>and allows you to identify and compare complex motifs easily. It is designed
>specifically to allow users to ask questions of about potential effects of changes
>made to the structure of a protein in key regions of structure. Iditis comes out of
>Prof. Janet Thornton's lab at University College London.
>>For more information see the review article
>in Chemical Design Automation News (Thornton & Gardner) vol. 8, no. 4 pg. 18.
>----------------------------------------------------------------
>Steve Gardner
>steve at gardner.demon.co.uk
How about info on distribution of this database, or an e-mail address for Dr. Thornton? I'll be
looking for the article, but if I can't find it some addresses will be helpful.
Thanks!
o-----------------------------------------------------------------------------o
| Peter Gegenheimer | pgegen at kuhub.cc.ukans.edu |
| Departments of Biochemistry and of Botany | voice: 913-864-3939 |
| University of Kansas | FAX : 913-864-5321 |
| 2045 Haworth Hall | "The sleep of reason produces |
| Lawrence KS 66045-2106 | monsters." Goya |
o____________________________________________|________________________________o