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amino acids per domain

Steve Gardner steve at gardner.demon.co.uk
Thu Jul 28 16:07:14 EST 1994


I am sorry, but I come to this thread late, and have lost the address of
Paul Yadlowsky who posed the original question.  I have a partial answer
from the Iditis relational database of protein structure that I wrote whilst
working in Prof. Janet Thornton's lab.  This is now commercialised by Oxford
Molecular, and I do work for them, so I beg forgiveness for posting this to
the main newsgroup rather than Paul direct.

I used a list of 99 non-homologous proteins containing 167 protein chains
(this being the list that I had available), and constructed a query to
return the number of chains with a given minimum number of residues. The results are
as follows:

Residues    No. Chains            Residues    No. Chains          Residues  No. Chains
--------    ----------            --------    ----------          --------  ----------
      25           163                 175            80               325          37
      50           155                 200            74               350          29
      75           143                 225            67               375          24
     100           130                 250            59               400          19
     125           107                 275            50               425          16
     150            95                 300            46               450          14
                                                                       475           0

I realise that this is only an indicative answer, but I hope that it helps.

----------------------------------------------------------------
Steve Gardner

steve at gardner.demon.co.uk




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