In article <3rcbb4$cee at lyra.csx.cam.ac.uk>,
Simon Brocklehurst (Bioc) <smb18 at mole.bio.cam.ac.uk> wrote:
>rvenable at deimos.cber.nih.gov (Rick Venable) writes:
>>> Given that the crystal is a somewhat artificial environment,
>> Sorry, can't let you get away with saying that - too many people
>will believe what you're saying. Crystal structures of proteins are,
>for the most part, excellent models for the structure in solution.
>_________________________________________________________________________
>|>| ,_ o Simon M. Brocklehurst,
>| / //\, Oxford Centre for Molecular Sciences
>| \>> | Department of Biochemistry, University of Oxford,
>| \\, Oxford, UK.
>| E-mail: smb at bioch.ox.ac.uk>|________________________________________________________________________
>>
To which one might add that proteins in crystals practically *are* in solution
since the percentage solvent is so high.
Regards,
Kip
--
Dr. Kenneth P. Murphy e-mail: k-murphy at uiowa.edu
Department of Biochemistry office: (319)335-8910
University of Iowa lab: (319)335-7936
Iowa City, IA 52242 FAX: (319)335-9570
