There are several programs available however, it depends
on exactly what sort of protein you are looking at.
For globular proteins some useful programs are:
1. Predict Protein (Rost and Sander, 1994)
2. Chou & Fasman [1978 (PROSIS program for PC's)]
3. Self Optimised Prediction
from Alignments (SOPMA) [Georjon and Deleage, 1994, 1995]
4. Protein Sequence Analysis (PSA) - good
graphical output (Stultz et al., 1993; White et al., 1994)
Good luck,
Ross De Gori