DNA model building
fedorov at uwchem.chem.washington.edu
Sun Sep 1 07:41:14 EST 1996
In article <Pine.SOL.3.91.960901004033.12370A-100000 at gate>,
wstzou at GATE.SINICA.EDU.TW (Wen-shyong Tzou) wrote:
> To summarize the responses of the questions about the methods to
> measure the nucleic acid parameters and/or construct a new nucleic acid
> from scratch based on a new set of parameters, it follows:
> 1) BIOSYM/MSI InsightII and MacroModel for DNA.
> 2) MC-SYM (http://www.iro.umontreal.ca/people/major/mcsym.html) for RNA
> 3) NAB for DNA (http://scripps.edu/case)
> 4) newhel93 for DNA available in PDB (http://www.gdb.org/hopkins.html)
> 5) Rasmol (http://www.gdb.org/hopkins.html)
IMHO, the most consistent and flexible set of DNA modeling software is
CURVES/JUMNA, developed by Sklenar and Lavery. You can easily manipulete
all structural parameters and build curved DNA, stem-loops, triplexes,
drug-DNA complexes and so on.
Cheers, Oleg Fedoroff, Ph.D.
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