On 13 May 1997, Kay Hofmann wrote:
> Is anybody aware of a study correlating temperature factor (or other
> metrics of local rigidity) to the position of the residue in a
> secondary structure element?
>> Intuitively, one would assume residues in the center of helices or
> beta structures to be much more confined than residues in structurally
> undefined loops. I am looking for a more quantitative treatment but
> could not find anything really relevant in the literature.
>
One of the papers on this subject:
R. B. Altman, C. Hughes, & O. Jardetzky. Compositional Characteristic of
Relatively Disordered Regions in Proteins. Protein and Peptide Letters,
1:120-127, 1994.
On-line version is available at
http://www-smi.stanford.edu/pubs/SMI_Abstracts/SMI-94-0514.html
Iosif Vaisman
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