On 13 May 1997, Kay Hofmann wrote:
> Is anybody aware of a study correlating temperature factor (or other
> metrics of local rigidity) to the position of the residue in a
> secondary structure element?
>> Intuitively, one would assume residues in the center of helices or
> beta structures to be much more confined than residues in structurally
> undefined loops. I am looking for a more quantitative treatment but
> could not find anything really relevant in the literature.
One of the papers on this subject:
R. B. Altman, C. Hughes, & O. Jardetzky. Compositional Characteristic of
Relatively Disordered Regions in Proteins. Protein and Peptide Letters,
On-line version is available at
Director, Computational Resource for (919) 966-7821 (office)
Molecular Sciences and Biotechnology (919) 966-3459 (lab)
University of North Carolina at Chapel Hill (919) 966-6919 (fax)
Chapel Hill, NC 27599-7360 http://www.unc.edu/~ivaisman