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3rd International Conference on Molecular Structural Biology

andreas kungl andreas.kungl at kfunigraz.ac.at
Fri May 21 09:43:13 EST 1999

The Biochemistry Subgroup of the Austrian Chemical Society
is pleased to announce the

Third International Conference on Molecular Structural Biology

which will take place in

Vienna, Austria
from September 8-12, 1999



Introduction to the ICMSB99

The First and the Second International Conference on Molecular
Structural Biology (ICMSB) took place in Vienna in September 1995
and 1997. Both conferences were very well received by all who took
part, including over 250 participants from more than 20 countries
The organisers are pleased to announce the Third ICMSB, which will
take place from 8th to 12th September 1999, and which will, like the
previous conferences, feature internationally renowned speakers.
The ICMSB99 will focus on topics covering a number of the most
exciting areas in the field, with the aim of bringing together
scientists from different areas. It will be opened by one of the most
outstanding scientists in the field of structural biology, Robert Huber,

and the following four days of sessions will include Folding and
Novel Structures, Advances in Microscopic Methods, Structural
Molecular Biology, Structure-Based Drug Design, and Prediction
and Simulation.


Vienna - An Attractive Conference Location

The ICMSB99 will be located at the Federal Chancellery in Vienna.
The city is a particularly attractive location for a conference,
with its combination of historical buildings, green parks, and
modern architecture. Some of the most famous city sights
include Schönbrunn Palace and the Hofburg, former homes
of the Habsburgs, St. Stephans Cathedral, and the colourful
Hundertwasser House. Also unique to Vienna is the Prater
park, with its endless green avenues and its funfair, featuring
the ´´Riesenrad´´ (ferris wheel). Of course, no trip to Vienna
would be complete without a visit to one of the many traditional
Viennese cafés, for a piece of the famous Sachertorte. An
´´Oldtimer-Tram´´tour around the Ringstraße will take
participants past many of the finest sights.


Organising Committee

A. Kungl, P. Andrew, A. Binder, S. Kristl, A. Schilk


Scientific Committee

C. Kratky, M. Sippl, A. Kungl, P. Andrew


In Cooperation With

Austrian Academy of Sciences
Austrian Federal Chancellery


Sponsored By

Austrian Airlines
Novartis Forschungsinstitut


Scientific Programme

The six sessions of the conference cover a wide range of topics
and experimental methods, which will be presented in the form
of plenary lectures, selected short oral communications, and posters.

Wednesday 8th:

Registration from 2 p.m. onwards

Honorary Lecture (followed by a welcome drink and snack)
Robert Huber (Max-Planck-Institute, Martinsried):
Diversity and Conservation in Proteolytic Enzymes and their Inhibitors

Thursday 9th:

Morning Session: Advances in Microscopic Methods
Werner Kühlbrandt (Max-Planck-Institute, Frankfurt):
Two Conformations of Membrane Ion Pumps
Hansgeorg Schindler (Linz University):
Single Molecule Microscopy Methods for Structural Biology
Helen Hansma (University of California, Santa Barbara):
Probing Biomaterials with the Atomic Force Microscope

Afternoon Session: Folding and Function
Alan Fersht (Cambridge University):
Minichaperones: Practical and Mechanistic Tools
Thomas Kiefhaber (Biozentrum Basel):
Speed Limit for Protein Folding
Peter Wright (Scripps Institute):
Structure and Dynamics of Unfolded Proteins and Protein Folding

Friday 10th:

Morning Session: Novel Structures
Michael Rossmann (Purdue University):
The Assembly of Viruses Examined by Combining Crystallography and
Cryo-electron Microscopy
Don Wiley (Harvard University):
Structural Studies of Viral Entry Mechanisms in Influenza, HIV-1 and
bola Viruses
Kurt Wüthrich (ETH Zürich):
TROSY and BSE - Recent Progress with NMR in Structural Biology

Afternoon Session: Structure-Based Drug Design
Siegfried Reich (Agouron Pharmaceuticals):
The Use of Protein Structural Information in Drug Design and
Some Examples
Keith Wilson (Vertex Pharmaceuticals):
Structure-Based Drug Design: Reality over Hype

Poster Session I

Saturday 11th:

Morning Session: Structural Molecular Biology
Stephen Cusack (EMBL Grenoble):
tRNA and Amino Acid Recognition by Aminoacyl-tRNA Synthetases
Robert Kaptein (Utrecht University):
Allosteric Interactions in Protein-DNA Recognition
Christoph Kratky (Graz University):
Structure and Mechanism of Enzymes with a B12 Cofactor
Paul Sigler (Yale University):
Structure and Function in Chaperonin-Assisted Protein Folding

Afternoon: Poster Session II (followed by the ´´Oldtimer-Tram´´ tour)

Sunday 12th:

Morning Session: Structural Genomics
David Eisenberg (UCLA):
Protein-Protein Interactions
Terry Gaasterland (Rockefeller University):
Using Patterns of Evolution Across Whole Genomes to
Support Structural Genomics Target Selection
John Moult (University of Maryland):
The Past, Present, and Future of Protein Structure Prediction
Wayne Hendrickson (Columbia University):
Prospects of High-Throughput Crystallographic Structure

Approx. 1 p.m.: End of Conference with Farewell Drink and Snack


Call for Posters

Interested participants are invited to submit abstracts describing
original work which has not been presented elsewhere. Abstracts
should arrive no later than July 10th, 1999. Authors will be informed
 about the provisional acceptance of the abstract by the end of July.
The presentation of the abstract as a poster will be confirmed, and
included in the Book of Abstracts when one or more of the authors
registers for the conference. Contributors of outstanding abstracts
will be chosen by the Scientific Committee to give a 15 minute oral

Poster Prize

A prize of ATS 2,000 will be awarded for the best poster contribution i
n terms of innovative results and presentation.


Abstract Submission

Camera-ready abstracts should be printed in good quality on a single
(A4) sheet of paper, within the area 16 cm wide and 24 cm long. The
title should be followed by the author(s) name(s), affiliation(s), and
address(es). Text should be in a 12 point font with maximum 1.5 line
spacing. Please send two unfolded copies of the abstract to the



The poster boards will be 100 cm (width) x 200 cm (height). Materials
poster mounting will be provided.


Conference Proceedings

The lectures and poster presentations will be published by the Austrian
Chemical Society in book form (with an ISBN number), and will be
distributed to the participants upon arrival at the conference.
copies of the Conference Proceedings can be purchased for ATS 300,-.


General Information

Exhibition: An exhibition of instruments, accessories, software,
literature, and other items is planned. Companies interested in
displaying their products are kindly requested to contact the
conference secretariat.

Social Events: The conference will be opened by a welcome drink f
ollowing the honorary lecture in the Federal Chancellery on the evening
of Wednesday, September 8th. On Saturday afternoon, the conference
participants will be taken on a tram tour of the city centre. Following
this, all participants are encouraged to visit a typical Viennese
(wine cellar) to enjoy the local food and wine (not included in the
registration fee). A further social event will be arranged for one
other evening, leaving one evening free to explore Vienna. In addition,
half day tours to some of Vienna´s best known sights will be organised
for accompanying people (dependent on participant number).

Registration (please contact the Conference Secretariat or our

Registration Fee               Before August 1      After August 1
Regular Participant           5.000 ATS              5.500 ATS
GÖCH Member*               4.000 ATS              4.500 ATS
Student**                         2.500 ATS              3.000 ATS
GÖCH-Students*/**          1.750 ATS              2.000 ATS
Accompanying Person        500 ATS                600 ATS

*Payment must be accompanied by proof of the remittance of the
´99-GÖCH membership fee
**Payment must be accompanied by proof of student status

The registration desk will be open from 2 p.m. on Wednesday,
September 8th.

The registration fee includes the Conference Proceedings and
participation in all scientific sessions, the welcome and farewell
drinks, lunch from Thursday to Saturday, coffee breaks, and
participation in the social programme (please note: the Heurigen
visit is not included). Accompanying people attend only the social
programme (welcome drink, tram tour, additional evening).

Accomodation is not included in the registration fee!

For accomodation, to register for the Heurigen evening, and to
book social events for accompanying people, please ask for the
flyer of the travel agency MONDIAL CONGRESS (at the conference
secretariat or at our homepage).

Remittance of Fees: Remittance must be made in Austrian
Schillings (ATS) payable to the Gesellschaft Österreichischer
Chemiker, Arbeitsgruppe Biochemie, Account Number
0043-19265/04 at Bank Creditanstalt, Bank Code 11000.
Payment is also accepted by sending a (Euro-)Cheque
to the conference secretariat or by filling in the credit
card form (Visa, Euro/Mastercard, Diners Club, and American
Express are accepted).

All charges due to bank transfer have to be paid by the
sender. The sender´s name and address have to be clearly
marked on every remittance.

Cancellation: Applications may be cancelled up to August 1st,
in which case 85% refund of fees already paid will be made.
It will not be possible to offer any refunds if cancellations are
made after that date.


Conference Homepage

Please visit our homepage at
for the latest update of the programme plus further information.


Key Dates

July 10, deadline for submitting poster abstracts
August 1, deadline for early registration fee
August 1, deadline for cancellation



Austrian Federal Chancellery (Bundeskanzleramt)
Radetzkystraße 2
A-1031 Vienna


Conference Secretariat

Dr. Andreas Kungl
Austrian Chemical Society (GÖCH),
Biochemistry Subgroupc/o Institute of Pharmaceutical Chemistry
University of Graz, Universitätsplatz 1, A-8010 Graz
Tel.: +43 316 380 5373, Fax: +43 316 382541
E-Mail: andreas.kungl at kfunigraz.ac.at

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