Computational Membrane Protein Structure
A postdoctoral position is open immediately at The University of
Virginia Medical Center for a computationally oriented molecular
biologist. The core project will be to develop and implement
computational approaches to determine three-dimensional folds of
proteins using data from site-directed spin labeling and EPR
spectroscopy. The project involves the application of distance geometry
methods with simulated annealing and molecular dynamics using a limited
number of experimentally determined restraints (probe mobility,
accessibility and inter-probe distances). The candidate will also have
the freedom to pursue an experimental line of research complementing the
computational studies.
Requirements:
- A PhD in Biophysics, Biochemistry, Chemistry, Physics or related
areas.
- Familiarity with distance geometry and simulated annealing methods is
required.
- Experience in structure determination using NMR methods is highly
desirable.
Applications including a CV, a description of research experience, and
the addresses and telephone numbers of three references should be sent
to:
Dr Eduardo Perozo
Department of Molecular physiology and Biological physics
University of Virginia Health Science Center
1300 Jefferson Park Ave
Charlottesville VA 22906
Email: eperozo at virginia.edu
Ph: (804) 243-6580
Fax: (804) 982-1616
