Mario Garcia wrote:
>> Dear all,
> We would need to predict by computer modeling the structure of
> the transmembrane domain of a channel protein likely to be composed by
> a 6 parallel helix bundle. Could anyone give us any advice or suggestion
> regarding methods and software specifically devoted on this subject? Any
> help will be welcome.
6TM? Definitely not one of the large family of 7TM proteins? There are
a couple of ways of modeling 7TM bundles, but I'm not sure how well
these will extrapolate to 6TM.
The pants way (definitely 7TM only):
http://www.expasy.ch/cgi-bin/sm-gpcr.pl
The real way (may be able to be extended to 6TM - but probably not!):
http://www.ysbl.york.ac.uk/~pavel/gpcr/7tm_1.html
Hope this helped?
Simon.
