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Modeling membrane proteins

Anurag Sethi sethi7ik at ccs.iitb.ac.in
Tue Jan 8 13:20:03 EST 2002


Hi everyone,
   I have got to model the structure of a protein in membrane for
which no template exist. Its structure in water is known and also,
there is some experimental data on the putative trans membrane
helices. However, the problems are:

1. The arrangement of helices in the membrane.
2. State of oligomerisation.

  How does one go about modelling the structure of the protein? Could
anyone please give me tips on how to proceed?

Thank you,
Anurag Sethi




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