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malaria synchrony

Steve Meshnick meshnick at sph.umich.edu
Fri Jul 29 13:00:33 EST 1994

     I think that the malarial fevers themselves act to synchronize the
parasites.  The high fevers might destabilize the outer membranes of
trophozoite-infected red cells (which are quite fragile), thus providing
an advantage for the parasites that are at the ring stage.   The periodic
fevers and synchronization might be an evolutionary adaptation to keep
parasitemias low, allowing the host to survive and keep infecting
mosquitoes.  There was an article about this in Parasitology Today
several years ago.

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