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Graduate Research Assistant: Evolution of ciliate genomes

Laura A. Katz LKatz at science.smith.edu
Fri Oct 5 07:28:56 EST 2001


  An NSF funded position is available to work on the evolution of
  ciliate genomes, focusing on the class Phyllopharyngea.  This
  ciliate class is comprised of four major groups, including the
  bizarre suctorians -- suctorians lack cilia as adults and give 'live
  birth' to ciliated embryos that they 'brood' in a variety of unusual
  structures.
   Like all ciliates, phyllopharyngeans contain two distinct genomes:
   a
  transcriptionally-inactive 'germline' micronucleus and a
  transcriptionally-active macronucleus.  We have already 
demonstrated
  that in at least some members of the class Phyllopharyngea,
  chromosomes in the macronucleus have been extensively processed to
  generate 'gene-sized' chromosomes (chromosomes that contain one
  gene, a short untranslated region and telomeres).

  The aim of this project is three fold:
  (1) use multi-gene genealogies to determine relationships among
  Phyllopharyngeans (2) describe the evolution of reproductive
  strategies in suctorians (3) further characterize the genome
  structure of the macronucleus and micronucleus in these taxa

  Methods include light microscopy, molecular techniques, field work
  (collections) and bioinformatics.  Facilities are also available for
  electron and confocal microscopy.  Applicants should have previous
  experience with basic microscopy and/or molecular biology.

  Graduate students working on this project matriculate through the
  Organismic and Evolutionary Biology program at UMass.
  http://www.bio.umass.edu/oeb/oeb.html

  Please contact me for more information.

  Laura Katz
  Faculty member: Graduate Program in Organismic and Evolutionary
  Biology, Umass-Amherst Assistant Professor: Department of Biology,
  Smith College Email: LKatz at Smith.edu Phone: 413-585-3825 --

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