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Xenopus tropicalis genetics meeting

David R. Shook drs6j at unix.mail.virginia.edu
Mon Apr 26 15:44:19 EST 1999

(please note: do not reply to drs6j, as I am not involved 
in running this meeting; see the e-mail address and web 
page below)

	We would like to invite those of you who might be interested in
studying the genetics of frog development to the following meeting:

Genetics of Amphibian Development:  Moving Into Xenopus tropicalis

University of Virginia, Charlottesville, VA,
Saturday, June 12, 1999 9 a.m. - 6 p.m.
X. tropicalis facilities tour and transgenesis workshop

Sunday, June 13 11 a.m. - 5 p.m.
preceding the SDB annual meeting June 13 - 18 in Charlottesville

	This meeting will focus on building a genetics community to complement
embryological and molecular research in Xenopus development. Presentations
will center on laboratory use of the more genetically-malleable Xenopus
tropicalis, and will include discussion of related issues, e.g., analysis
and manipulation of ploidy in Xenopus, and recent advances in transgenesis.
Special emphasis will be placed on learning from the zebrafish community's
experience. Following the presentations, there will be an open caucus to
discuss generating shared genetic research infrastructure, such as genetic
and physical maps, stock centers, and mutagenesis strategies. Attendees are
encouraged to present posters speculating on how they would like to use
specific genetic strategies. On Sunday, June 13, there will be a tour of
the X. tropicalis facility at U.Va. and a transgenesis workshop. For more
information or to register, email xenopus at virginia.edu or visit the X.
tropicalis website at http://minerva.acc.Virginia.EDU/~develbio/trop/.


Session I: Building A Genetic System For The 21st Century

9:00 a.m. - 12:30 p.m.

Introduction to Xenopus tropicalis
Rob Grainger
Univ. of Virginia

Review: Genome Manipulations and Mutants in Amphibians
Darcy Kelley
Columbia Univ.

Genetic Screens for Vertebrate Developmental Genes
Mary Mullins
Univ. Of Penn.

Contrasts Between X. tropicalis and X. laevis Major Histocompatibility				  
Complex: the Influence of Polyploidy on Gene Silencing
Martin Flajnik
Univ. of Maryland

Embryology of X. tropicalis
Ray Keller
Univ. of Virginia

Laboratory Husbandry of X. tropicalis
Nick Hirsch
Univ. of Virginia

12:30  Lunch and posters

Session II:  New Approaches to Manipulating Amphibian Genomes

1:30 - 4:00 p.m.
Towards Amphibian Developmental Genetics:
Lessons From Zebrafish					  
Len Zon
Harvard Univ.

Transgenesis in Xenopus:  Present and Future
Enrique Amaya
Wellcome/CRC Inst.

'Gene Trap' Insertional Mutagenesis of X. tropicalis
Odile Bronchain
Wellcome/CRC Inst.

Strategies for Inducible Control of Gene Expression in 
X. tropicalis							  
Lyle Zimmerman
Univ. of Virginia

Transgenic Analysis of Opsin Promoter and Function
Barry Knox
SUNY Syracuse

Saturation of Zebrafish Notochord Mutations: 			
Can new loci be identified in Xenopus Tropicalis?		  
Derek Stemple
NIMR, Mill Hill


Caucus discussion: Building community resources and infrastructure for
genetic research
(Chuck Kimmel, University of Oregon; Doug DeSimone, University of Virginia;
Peter Vize, University of Texas, moderators)

6:00 - 12:00
Shuttle bus every half hour to/from evening social

Sunday, June 13
11:00 a.m.	Coffee
11:30 a.m.	X. tropicalis facility tour
1 p.m.-5 p.m.	X. tropicalis Transgenesis workshop

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