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(please note: do not reply to drs6j, as I am not involved
in running this meeting; see the e-mail address and web
page below)
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Colleagues,
We would like to invite those of you who might be interested in
studying the genetics of frog development to the following meeting:
Genetics of Amphibian Development: Moving Into Xenopus tropicalis
University of Virginia, Charlottesville, VA,
Saturday, June 12, 1999 9 a.m. - 6 p.m.
X. tropicalis facilities tour and transgenesis workshop
Sunday, June 13 11 a.m. - 5 p.m.
preceding the SDB annual meeting June 13 - 18 in Charlottesville
This meeting will focus on building a genetics community to complement
embryological and molecular research in Xenopus development. Presentations
will center on laboratory use of the more genetically-malleable Xenopus
tropicalis, and will include discussion of related issues, e.g., analysis
and manipulation of ploidy in Xenopus, and recent advances in transgenesis.
Special emphasis will be placed on learning from the zebrafish community's
experience. Following the presentations, there will be an open caucus to
discuss generating shared genetic research infrastructure, such as genetic
and physical maps, stock centers, and mutagenesis strategies. Attendees are
encouraged to present posters speculating on how they would like to use
specific genetic strategies. On Sunday, June 13, there will be a tour of
the X. tropicalis facility at U.Va. and a transgenesis workshop. For more
information or to register, email xenopus at virginia.edu or visit the X.
tropicalis website at http://minerva.acc.Virginia.EDU/~develbio/trop/.
Program
Session I: Building A Genetic System For The 21st Century
9:00 a.m. - 12:30 p.m.
Coffee
Introduction to Xenopus tropicalis
Rob Grainger
Univ. of Virginia
Review: Genome Manipulations and Mutants in Amphibians
Darcy Kelley
Columbia Univ.
Genetic Screens for Vertebrate Developmental Genes
Mary Mullins
Univ. Of Penn.
Contrasts Between X. tropicalis and X. laevis Major Histocompatibility
Complex: the Influence of Polyploidy on Gene Silencing
Martin Flajnik
Univ. of Maryland
Embryology of X. tropicalis
Ray Keller
Univ. of Virginia
Laboratory Husbandry of X. tropicalis
Nick Hirsch
Univ. of Virginia
12:30 Lunch and posters
Session II: New Approaches to Manipulating Amphibian Genomes
1:30 - 4:00 p.m.
Towards Amphibian Developmental Genetics:
Lessons From Zebrafish
Len Zon
Harvard Univ.
Transgenesis in Xenopus: Present and Future
Enrique Amaya
Wellcome/CRC Inst.
'Gene Trap' Insertional Mutagenesis of X. tropicalis
Odile Bronchain
Wellcome/CRC Inst.
Strategies for Inducible Control of Gene Expression in
X. tropicalis
Lyle Zimmerman
Univ. of Virginia
Transgenic Analysis of Opsin Promoter and Function
Barry Knox
SUNY Syracuse
Saturation of Zebrafish Notochord Mutations:
Can new loci be identified in Xenopus Tropicalis?
Derek Stemple
NIMR, Mill Hill
Refreshments
4:00
Caucus discussion: Building community resources and infrastructure for
genetic research
(Chuck Kimmel, University of Oregon; Doug DeSimone, University of Virginia;
Peter Vize, University of Texas, moderators)
6:00 - 12:00
Shuttle bus every half hour to/from evening social
Sunday, June 13
11:00 a.m. Coffee
11:30 a.m. X. tropicalis facility tour
1 p.m.-5 p.m. X. tropicalis Transgenesis workshop
