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Diploid Viruses?

Heather D. Mayor hmayor at bcm.tmc.edu
Thu Oct 27 13:53:45 EST 1994

In article <38oj6c$es6 at hermod.uio.no>, ohungnes at bioslave.uio.no (Olav
Hungnes) wrote:

>" Furthermore, the retrovirus particles contain two copies of the genomic RNA.  >They will be "homozygous" if originating from a cell with only one provirus, >and may be "heterozygous" when incorporating transcripts from two different >proviruses ( probably random) in a mixed infection setting.  Recombination >between the two copies seems to happen frequently: "

> Rearrangements and homologous recombination in retroviruses is quite 
> common. The frequency of recombination is so high that two sites 1 kb 
> apart is reported to segregate independently. 
> Olav
> -- 
> _______________________________________________________
> Olav Hungnes                 olav.hungnes at embnet.uio.no
> National Institute               Phone  (+47)22042200
> of Public Health                 FAX    (+47)22353605
> Oslo, NORWAY
> _______________________________________________________

Where is the published information that recombination between the two
copies of the retrovirus RNA occurs frequently?

H* Heather D. Mayor           *D*  hmayor at mbcr.bcm.tmc.edu    *M           
H* Department of Microbiology *D*           OR                *M
H* Baylor College of Medicine *D*    hmayor at bcm.tmc.edu       *M
H* 1 Baylor Plaza             *D* VOICE 713-798-4929          *M
H* Houston, TX 77030  U.S.A.  *D*   FAX 713-798-7375          *M

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