In Article <mikep.295.000B0589 at uniwa.uwa.edu.au>, mikep at uniwa.uwa.edu.au
(Michael Poidinger) wrote:
(snip out poliovirus eradication congratulations)
>>Subject: Re: Polio vaccination
>>Yes, well this is a bit of a misguiding comment. Wildtype polio has been
>eliminated. Attenuated vaccine strains still run strong in the Western World,
>and they can occasionally cause problems. There was a man that contracted
>polio from changing the nappies on his baby last year, after said baby was
>vaccinated but the vaccine reverted. Polio virus, in one form or another,
>will be around for a while to come.
>I vaguely remember a paper in Nature (?) several years ago in which the
author monitored the infectivity of the virus his baby shed after (Sabin)
immunization. As I remember, he found the reversion rate was just slightly
slower than the rate of neutralizing antibody production. Does anyone have
the reference?
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Mark A. Williams
Cytel Corporation
mwcytel at nic.cerf.net
