I read an article (not written by virologists) suggesting that the
interferons induce a broad spectrum antiviral response other than that
which can be explained by a cell-mediated immune response.
Is a broad spectrum response observed?
Or is it dependent on the host/virus?
Can anyone tell me (or point me to a concise review) what the
breakdown is for interferon alpha, beta, gamma; i.e. potency of
any specific or broad spectrum antiviral response.
I know gamma interferon is involved in cell-mediated immunity and up
regulates antibody production (textbook stuff).
I'm interested for responses that aren't related
to the production of antibodies, e.g. ones observed in cell culture.
Thanks in advance.
Christopher Hogue
NRC-IBS Bldg. M54
Ottawa Ont. Canada K1A 0R6
hogue at biologyM54.lan.nrc.ca || ai473 at freenet.carleton.ca
