Interested in influenza? look up "cold-adapted influenza vaccine", it was
developped by Dr. Maassab, University of Michigan, in the early 70's.
You'll find a gazillion papers byhim and alos by Murphy and others who
have been invilved in testing its efficacy in various populations
including adults. If you need any moreinformation feel free to email me at
parkin at aviron.com
Neil.