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Influenza Virus Info...

Dr. Zhao-Hua Zhong zhongzh at public.hr.hl.cn
Sat Dec 28 22:38:51 EST 1996

Dear Kylie Smith:

The specificity of haemagglutination inhibition assay (HIA) for the 
detection of influenza antibodies in sera can be considered to be 
very good because the HI antibodies are induced by the viral 
haemagglutinin (in the surface of viral envelope) which determines 
the subtypes of influenza viruses. 

Although many viruses, especially the myxoviruses, have haemagglutinin
in their envelopes, you will not confuse when you are doing HIA 
because the standard virus strains must be used as the known antigens. 
No further control is needed except the haemagglutination control.

Happy New year!

Zhao-Hua Zhong
Harbin, China

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