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HIV infection of T4

Giovanni Maga maga at vetbio.unizh.ch
Tue Nov 5 20:14:52 EST 1996


In article <54tms9$mti at net.bio.net>, "h1oq" <h1oq at unb.ca> wrote:

> I am looking for some help or direction in trying to locate the latest
> information in regards to HIV infection of T4 cells. In particular, CD4
> recognition and the possibility that some people with genetically altered
> CD4 have shown a certain amount of immunity to HIV.
> 
> Anyone with ideas or help please post a response or EMAIL me directly to
> h1oq at unb.ca
> 
> Thank-you.
> Jason Reath
> University of New Brunswick, Canada

I think you are referring to the recent findings about the chemokine
receptor CC-CKR5 as a cofactor for HIV entry and the finding of elevated
resistance to infection in individuals carrying a homozygous mutation
(deletion) in the CC-CKR 5 gene. I do not have now the references at hand,
however there were two Nature papers and a Cell paper recently. Try a
Medline cross-search with chemokine/CC-CKR5/HIV as subjects and Paxton as
author.
Can always have a look and e-mail to you the ref. later on.
Hi, Giovanni.





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