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MHV and tumour cell lines

tim at besancon.net tim at besancon.net
Wed Jul 29 14:40:17 EST 1998

Hi everybody,
We work on murine bone marrow transplantation using WEHI and A20 cells
in a GvL model. Since the introduction of these cells we have observed
atypical survival rates after BMT. We suspect viral contamination of the
tumour cell lines (most probably MHV, after the histopathological
analysis). Does anybody have some similar experience or advice on this
situation? Any reference on viral contamination of murine tumour cell
lines will be also welcome.

Marcelo Bittencourt, MD
Lab. TIM, ETS de Franche-Comt=E9

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