Shelly,
The infectivity potential of the virus can decrease with a freeze thaw
or other inactivating steps. The actual virus particle count probably
does not change. To avoid titer losses: aliquot samples, include a
stabilizer or freeze samples.
Regards,
Keith
Shelly Ogiste wrote:
> Hi I was hoping you could help me with a question. How can you "lose
> titer" in a freeze thaw cycle? If I take a liquid and repeatedly freeze
> it and thaw it, how is the concentration going to change?
>>>>>> Shelly
